By birth, babies that will be diagnosed as food allergic are already different in immune function. Click on the link to read abstract, and then read my commentary below… https://stm.sciencemag.org/content/8/321/321ra8
“Now, Zhang et al. report that infants who later developed food allergy had altered immunity at birth. Cord blood from these infants had more monocytes compared with CD4+ T cells and decreased numbers of regulatory T cells. Moreover, the monocytes from food-allergic infants secreted more inflammatory cytokines than those from healthy infants. These cytokines suppressed interleukin-2 (IL-2) expression by CD4+ T cells and skewed differentiation of these cells to a nonclassical T helper 2 (TH2) phenotype. Anti-inflammatory strategies should therefore be considered in preventing food allergy in these individuals.”
Discovery of the mechanism by which this occurs may eventually be useful; proof that this happens is helpful. BUT this is hardly new to anyone who has been reading my work since 1980, or Food for Thought in 1982. What happens in pregnancy, including food allergen exposure, affects what happens after. So what has affected your mother affects you. So the intergenerational effects of infant feeding are involved in making the next generation allergic. Which is what I and innumerable breastfeeding parents have been saying since the 1980s. To me, this is further proof of my Milk Hypothesis, since infant nutrition is indeed, as key researchers have said, the single postnatal influence on lifelong development.
Read Milk Matters with this little bit of proof added! then think about the foods for babies: breastmilk with its huge range and variety of anti-inflammatory and repair factors, and formula, with its huge range of pro-inflammatory factors, from the advanced glycation end products produced by heat to the alien proteins and fats, to the unnatural industrially-made carbohydrates, the additives with traces of extracting chemicals…… and its absence of those modulating factors in breastmilk. What other anti-inflammatory strategy is universally available?
It is ignorance of these basic biological facts which allows formula advocates to fantasize that it doesn’t matter whether you formula feed so long as you have a clean water supply, are literate and take care. ALL babies not breastfed are being exposed to pro-inflammatory pressures that result in – guess what – the range of western epidemics with their roots in inflammation, from CVD to auto-immune disease. SOME of those babies are lucky in there genetic inheritance and don’t suffer. but ALL are at needless risk.
This draft sat here for a year, but is still valid – please share this information.